Wish I knew about this sooner!! No side effects what so ever. I am a 60 year old woman who had loss of sex drive, not to mention it hurt even if I tried. This made me feel like a 20 yr old again!!
Shared reviews and ratings
Most Helpful
Most Recent
Highest Total Rating
High Satisfaction
Low Satisfaction
No data
Estradiol Cream | 65-74 | Female | On medication for 1 to 6 months | Patient
7/27/2024
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
I am not exaggerating when I say this cream saved my life. I could no longer live with my whole pelvic area on fire. After many different antibiotics for my chronic bladder infections/UTIs (1yr) I could no longer function day to day. Prescriptions no longer worked. I no longer wanted to live with hot coals burning me inside.
I had immediate relief after being on the cream for only a few days. And I now use it 3 times a week to maintain and hold back my ITIs, the burning, the pain. I will be for ever grateful to my FNP that prescribe this for me. Read More Read Less
Report this post
Anon | 55-64 | Female | On medication for 1 to 6 months | Patient
7/4/2024
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
Was having to get up five or six times a night to go to the bathroom. From night one, I’ve only had to get up once. Sleeping soundly, waking in the morning ready to go!! It’s been years since I felt like this!! 61 years old - wish I hadn’t waited so long.
1
Report this post
Anonymous | Female | Patient
3/31/2024
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction
I tried using Estradiol because Premarin was costing a fortune. I used it maybe 4 times, burned like fire. Nothing works for me but Premarin.
1
Report this post
Carol | 55-64 | Female | On medication for less than 1 month | Patient
2/13/2024
Condition: Postmenopausal Urethral Atrophy
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction
After only one use I experienced blinding headaches, which I don't suffer from.I also felt extreme fatigue and generally unwell . Feelings of getting either candida or an UTI. I took for about 17 days ,even my pelvic gloom felt swollen and strange .Won't be taking anymore
1
Report this post
Lillie | 75 or over | Female | On medication for 10 years or more | Patient
1/16/2024
Condition: Postmenopausal Urethral Atrophy
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction
After using estradiol vaginal cream before bed, the next day I have more frequent trips to bathroom to urinate.almost feels like a UTI. Then the next day will be ok. I’ve been using the cream 10 years. Just noticing this side effect. Anyone else experiencing this?
1
Report this post
Anonymous |
10/27/2023
Condition: Other
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction
Doctor recommended this cream three times a week after i had my yearly exam. I started it in June 2023. Up to now October 2023 my hair is breaking off badly! And it turned curly in the back only. I can’t sleep at night at all. I stay awake till 3:30-4:00am. It makes it difficult for me to get up for work. I wish I would have NEVER put this in my body.
1
Report this post
disappointed | 75 or over | Female | On medication for 2 to less than 5 years | Patient
5/31/2023
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction
Been using Estradiol creams for several years. My pharmacy switched to this brand and I started to have problems. Cream worked for few weeks after opening new tube, then stops being effective. Happened with 3 different tubes, amd switching to different pharmacy to get different brand.
1
Report this post
DAW | 45-54 | Female | On medication for less than 1 month | Patient
3/1/2023
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction
I got extreme allergic reaction after one suppository that led to urinary tract infection (UTI) the next day.
1
Report this post
June | 55-64 | Female | On medication for 1 to 6 months | Patient
12/3/2022
Condition: Other
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction
Messy on my panties, had to buy liners. I have developed breast nipple tenderness “Bad”. But I have noticed that I have had more Sexual arousal when my husband touches me between the legs ?? & that is Absolutely what I want going for! A Boost in my libido. Yea!!
1
Report this post
April | 55-64 | Female | On medication for less than 1 month | Patient
10/21/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
I am on my 2 weeks with the pill and I notice the difference the first time I used it! I am not dry down there like a sandbox and my husband also can tell the difference.
I use the pill insert because it is less messy and I don’t have any luck with creams.
1
Report this post
Celia | 45-54 | Female | On medication for less than 1 month | Patient
10/17/2022
Condition: Postmenopausal Urethral Atrophy
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction
Estradiol made me feel like I was on drugs. I used it for two nights and I felt the worst fatigue ever and it made my vagina burn and my face and lips was burning. I don't recommend this cream to no one. It's a killer
1
Report this post
HappyCamper | 55-64 | Female | On medication for less than 1 month | Patient
9/14/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
I have been using estradiol cream for about 3 weeks. I used 1 gm daily for 2 weeks and now I use 1 gram 3 to 4 times weekly. I had total relief from painful sec by the second week. My body feels normal and sex is enjoyable again. I would also like to mention that I had gone without sex for almost 20 yrs. I stopped having sex when I was 40. I am 59. I had started having menopause symptoms at 51. Just started being sexually active again in July, 2022. I found sex to be painful before estradiol even though I was not dry down there. I guess my vaginal walls had thinned. Now with estradiol I am back to normal. It is definitely worth it. I work out too. Dye my hair and looking good at 59. Feeling confident again.Read More Read Less
1
Report this post
Knightstar3770 | 45-54 | Female | On medication for less than 1 month | Patient
5/31/2022
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction
I took the medication 3x a week and developed and extreme rash that was both painful and itchy. My skin looked like raw meat, it was really bad.
1
Report this post
Grace | 65-74 | Female | On medication for 2 to less than 5 years | Patient
4/19/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction
After the initial loading dose, I am using 1 g 3x per week. It's an improvement, but wasn't sufficient for the atrophy. After a couple of months, the painful dryness improved, but I still couldn't tolerate a speculum for a pap smear, let alone sex. What tipped the balance to full function was sea buckthorn capsules (google sea buckthorn and vaginal atrophy to see "Effects of sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study") and the use of a vaginal dilator to stretch constricted tissue at the opening. Read More Read Less
1
Report this post
anonymous | 45-54 | Female | On medication for less than 1 month | Patient
1/27/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction
I got a yeast infection shortly after starting this. Apparently this is common, but after 6 weeks and 2 dr visits to clear it up, I am done with estrogen cream. I have switched to Vitamin E suppositories (often prescribed for cancer patients who can't get estrogen). I am in the perimenopause phase.
1
Report this post
Patti | 55-64 | Female | On medication for 1 to 6 months | Patient
12/18/2021
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction
I've been taking this medication for over a month. I'm not as dry as I was prior to taking it but my skin "between my labia majora & labia minora" still easily cracks/tears and is still irritable from time to time.
1
Report this post
JG Florida | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
10/7/2021
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction
Sex was painful and my sex drive was low. This started to work right away maybe a week after starting it. It was and is an amazing difference. I noticed no real side affects. I gained some weight after I started it but think it was due to just eating more junk food. I stopped doing that and lost the weight. I really appreciate this medication.
1
Report this post
L Pow | 55-64 | Female | On medication for 1 to 6 months | Patient
8/10/2021
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction
This vaginal cream has helped me a lot and I am no longer dry. However, I have noticed weight gain. I’m up 8-10 pounds in just a few months.
2
Report this post
Di | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
7/16/2021
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
As others have said sex was no longer a great thing due to pain with intercourse. It took appx a month and I'm back to the old me :)
2
Report this post
Leesers | 55-64 | Female | On medication for less than 1 month | Patient
6/27/2021
Condition: Postmenopausal Urethral Atrophy
Overall rating 1.3
Effectiveness
Ease of Use
Satisfaction
Was told to apply a pea sized amount to the vaginal opening 3x weekly. "Just leave it at the opening with your finger, and your body will know what to do from there." It didn't. It should have melted towards the inside, but instead, it melted outside, covering the urethra. I had a mess every time I urinated after using the product.
IMPORTANT INFORMATION ABOUT USER-GENERATED CONTENT ON WEBMD
The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.