This medication has been a life saver for me. I have been on several medications before this, and none have been as helpful as Effexor. (I also take Wellbutrin.) I've been diagnosed with Borderline Personality Disorder, Manic/ Depressive, General Anxiety, Social Anxiety, Seasonal Anxiety, Major Depressive Disorder, PTSD and I show signs of Schizophrenia. Effexor does have many negative side effects. The side effects that I suffer from are nausea, loss of balance, sweating, dry mouth, no sex drive, constipation, tremors and excessively yawning (in the beginning but no longer). If I accidentally miss a dose, the withdrawals are intense. Mania, tremors, headaches, extreme sweating. But it clearly states in the medication description that this will happen if you miss a dose, and it directs you to NOT quit this medication suddenly. If you complain about the side effects of quitting cold turkey, that's your own fault. You were clearly instructed not to do so. While the negative side effects can be harsh, the positives are worth it. I can keep my intrusive thoughts to a minimum, my mind doesn't race a mile a minute, my impulsive behaviors are very minimal and controllable. I have control over my outbursts of anger and I no longer lay in bed all day. I now have the motivation to cook a meal, actually partake in activities with my children, to clean my house and visit with friends and family. I don't have sudden suicidal urges, I can think rationally. I go to work everyday instead of hiding in my home and going ghost on everyone for weeks at a time. I am generally happy. Do I have my moments? Yes, absolutely. But they are far and few between and can be easily identified and diffused. My marriage and my family life have been positively impacted. My overall quality of life has greatly improved. I can go through some uncomfortable side effects if it means I have a higher quality of life. Best of luck to anyone suffering. Read More Read Less