I am a self-medicater, advised by my local pharmacist to take a combination of Motrilium, Opremazole and Sucralfate after at least 14 years of GERD. My acid reflux was so unpleasant, I've had to quit eating dinner in 2013, and do not eat any solid food after 1pm. The diet suits me fine, but the lingering acid reflux does not. I've had an asthma inhaler bedside since 2007, just in case gastric acids creep up my esophagus and shut down my lungs during sleep. This has happened about 10-15 times over these years, though less frequently since I've quit eating dinner. I've been gobbling up antacids (Tablets containing Aluminum Hydroxide & Magnesium Carbonate) for years. My brother has had surgery 3 times for the same problem; I've willfully avoided surgery for it. I'm just completing 1 month taking these meds, moving into my 2nd month. I stopped the Motilium after 3weeks. I continue with a half dose of Omeprazole (20mg daily instead of 40mg), and the full dose of Sucralfate (4g total per day). I've found the combination highly effective thus far, but am highly aware of the adverse side effects, to I'm trying to use it both sparingly and strategically, for the shortest time possible. All 3 of these meds have highly complex dosing and drug interaction requirements. I'm not sure if the Motilium is necessary at all, especially considering the possible side effects. I'm still assessing when I want to take my single dose of Omeprazole, since I halved the dosage at the 4-week point. It seemed like taking it in the morning was recommended, but I'm not so sure. My problem is worst at night, but if I want to reduce acid production in the stomach, it seems I may want to do so about 1 hour before drinking my fruit juice dinner. That should help me when my GERD is worst, and I can still take the Sucralfate in the complete absence of food & meds in my stomach both morning and night. I will soon reduce those Sucralfate doses from 2g each to 1g each and see how it goes, all the way out to the end of the 8-week period. I now have 4 weeks to consider my post-treatment plan: Continue reducing dosage? Stop completely? Proceed with reduced, intermittent doses, perhaps half doses, 1-3 times per week? When we walk into a pharmacy, we absolutely must keep front of mind the fact that every single product for sale -- except water -- is harmful to us. We buy & consume these products as the result of our simple, informal risk/reward analysis, that we absolutely must perform, lest we run the risk of some nasty side effects that may put us in the hospital or even the graveyard. Omeprazole and Sucralfate are highly effective, especially when used together (but you can NEVER take them at exactly the same time). They are certainly NOT easy to use. The patient and/or caregiver must be extremely attentive, cautious, and vigilant in order to get the maximum benefit, with the lowest risk of side effects that may be quite severe.Read More Read Less