User Reviews for Trulicity subcutaneous

I started at .75 dosage and had mild nausea for a couple of months. Dosage has been increased to 1.5, and the nausea did not return. I have lost 16 pounds and my A1c went from 8.5 to 6.5. Very happy!

Have used Trulicity 1.5 for nearly a year (10 months?). Other than the horrible expense, this medicine is extremely easy to use, nearly painless 1x week injection. Drug company does have a rebate program where I receive $150 back after submitting invoice, but still way out of range to what it should cost. But I will keep using it. Previously used Bydureon -- NEVER AGAIN!!

Its been causing me severe constipation. It might cause more problems. Constipation doesn't let me sleep, concentrate on my work, severe pain in the stomach make me feel that it caused me more issues in my body. My sugar level is not affected that much. I was in normal routine of going to gym, but since I started taking Triplicity, my energy level is so low that I want to just relax all the time. Lost about 8 kilos in 3-4 months. U believe their study is incomplete. Doctors take a note.

3 months in, and no side effects. Feel better after getting off metformin. Appreciate the pen, easy to use. Wish it was out sooner.

Have been on T for approx 9 months.Started with .75 and minimally nautious.First 4 mo. Experienced very minimal nausea. Dose was raised to 1.5 after approx 5 mo.due to A1C was still 6.5 and weight loss after 15 lbs had stopped.Now have lost 26 lbs (8 lbs from my goal)but the often nausea is still there.I get very loose stools at least once a weak.Would be the perfect drug without those side effects.I will live with them for now.

Liked the drug and ease of use. Side effects were unbearable..and they appeared to be cumulative. Abdominal pain, GERD , constipation. Each week got worse so I had to stop..but I liked the appetite suppressant.

may cause thyroid issues hene dont take

Started with two weeks of 75mg and then started on the 150mg for three weeks. I constantly had an upset stomach, usually puke at least once a week, had signs and lab tests after indicated results similar with pancreatitis. I have not puke so much and felt so terrible ever. Lost weight tho, 500 cal a day of crackers, yogurt, water will do it and still puke it up. When I felt good I felt real good but never for long. I like the approach to it but may have increased dosage to soon

I heard about this shot from my Dad who also struggled with T2 Diabetes (his A1C is now a 5!). I just took my 4th shot today (0.75 mg) and I feel the best I have felt in YEARS!! My blood sugar has dropped significantly and I have more energy. I have also lost 14 pounds since starting. When I first started, I did have some nausea and cramping but it has become less with every dose I take. My appetite has changed and I have noticed that the first few days after my shot, I have virtually no appetite. I simply remind myself to at least eat a small meal and I feel fine. Read More Read Less

Easily my most horrible medication experience. Had expected appetite loss, constant bloated feeling and daily nausea. Day after 4th shot, my digestive system shut down completely. I am praying for the last dose to wear off so I can defecate once again. Eating only liquids for past 2 days & constipation treatments have produced no results.

I must say that after reading reviews here, I was terrified to begin Trulicity. But once a week has been a liberating experience rather than twice-daily Byetta. I feel so free! I just started my third week, increasing now to the 1.5 dose. As far as I can tell, I've experienced none of the side effects mentioned. A.M. fasting BS numbers are definitely lower. I haven't noticed a change in appetite either way. I experience mild nausea on occasion, as well as minor diarrhea, but I've had that for some time so no change there. In fact, I have taken Pepto-Bismol as suggested by one of the reviewers, and that seems to have helped. I can't wait for next A1C. I expect good improvement. So far good results.Read More Read Less

This drug truly works for me, Easy to use, A1C down from 11 to 5.1 in 4 months

My doctor asked me to try this medication and it was a game changer for me. I felt better than any other medication I've previously or since tried. My A1C went down, my daily checks were good, I started losing weight and I had energy unlike I'd had in years prior. I was highly impressed with it's effectiveness. I didn't experience a lot of issues mentioned here... I regularly deal with nausea so that wasn't new for me, but I can confirm that it is a possible side effect. The worst thing about Trulicity is that my insurance refuses to pay for it. My mother is now having the same problem with Medicare. The drug works, the insurance not so much.Read More Read Less

I love this drug! I had some nausea at first, but now in my 6th month of taking it I rarely get sick. Appetite has decreased significantly and have lost 28lbs so far. My MD decreased Metformin in half about 2 months ago and may need to decrease Lisinopril also. A1C went from 8.6 to 6.2. My only issue with the drug is the itching and redness at the sight of injection, but will keep taking it because nothing has ever worked for me like this drug!

Trulicity has been a life changer for me. I have been on it for about 10 months and have lost 42 pounds. It has decreased my appetite dramatically. I used to be hungry all the time. Now, if I over eat, it is for psychological reasons only, never for hunger. I have had nausea all along but only very early in the morning, one or two days after my injection. Then I'm fine. Anti-nausea meds my doctor prescribed were very helpful but now I just go it on my own. I've learned to alter some of my routines to help prevent it - like not taking all my meds right before bedtime. Constipation has been an issue at times, but it is helped dramatically by eating yogurt daily and stool softeners occasionally. Before Trulicity my A1C was up to 14, now it is below 7. This is the most effective treatment I have ever experienced and I am grateful for it.Read More Read Less

This medication has been great. The first month was difficult but the results were really good for lower bs. Increased the dose and doing well. I have been on this for 6 months.

3days after first dose of Trulicity I had projectile vomiting and sulpher burps, constant nausea and diarrhea for 3 days. After next shot the same thing. I didn't want to quit the medicine as my fasting blood sugar were 90-120 for the first time in years. Then I discovered the answer, Pepto-Bismol. It's like a miracle. Stops the rotten egg burps, nausea, vomiting and diarrhea. Now I just take a dose of it right after my shot and again the next morning if I feel queasy. I'm a nurse and can't believe that good old Pepto works so great. Just be aware that it might make you tongue and bowel movements black. Read More Read Less

I had been on Glucophage for years and it finally quit working. I was told to take this with the Glucophage 2 mths ago. It lowered the BS from 350 down to 190 so increased the dose per Dr. and now is even lower. The side effects are terrible and hope the nausea and tiredness ends. I feel like I will vomit almost constantly. Bloating also. Not sure I can continue on it due to feeling like crap all the time. I am hoping the side effects will end. As for weightloss I have had that but it is because I take a few bites of food and feel ready to throw up.Read More Read Less

First dose went smoothly. Next day terrible headache and my joints began to hurt. Several weeks in now and I feel like I've been run over by a truck. My joints hurt terribly. I am so sleepy and tired all the time even though my routine has not changed. I have diarrhea daily and have actually gained weight. My numbers have not gone down and I've discussed coming off but my doctor wants me to keep trying. I think I need another opinion.

Only two days into this regimen, and I am experiencing almost certainly what must be the side-effects: constant flatulence, loss of appetite-- no food sounds particularly good to me at present-- and a constant belching which brings up a nasty, stale taste in my mouth, which actually reminds me of stale blood, truth told.