User Reviews for Trulicity subcutaneous

I have been on trulicity for over a year. I am taking the 4.5 dose. I usually get nausea when I start a new box, but that goes away with in the first 3 days. My A1C has went from a 9.1 to a 7. I have lost 75 pounds in a year. I love it. It’s the best thing ever. I take it the same time and day each week. I have been taken off metformin. I feel great and have tons of energy.

This is the second time I've tried Trulicity. The first time I stopped it because my family doctor at the time, stated because I was only pre-diabetic, the benefits did not outweigh the risk. This time however, my eGFR was highly elevated and was recommended again by my endocrinologist. I'm on my second week... I have absolutely no appetite, heartburn and indigestion are my constant companion, as well as nausea and vomiting, which seems to subside after about three to four days. I believe if I continue to take this medication, things are only going to get worse. Therefore, I will be calling my doctor and telling her that I no longer wish to take this medication.Read More Read Less

I have been taking trulicity 1.5 for 3 weeks now. The first two weeks were horrible. Constantly, full and upset stomach, vomiting despite barely eating anything. The third week isn't much better. I still feel too full to eat and always slightly sick to my stomach. I don't see how this medication is any different than just eating less, to reduce glucose. I have been a vegetarian most of my life and eat a very healthy diet, but still got diabetes. I have lost 10 lbs in 2 weeks from eating a handful of pretzels each day with another snack because its all I can tolerate. This does not seem healthy to me!Read More Read Less

Started first Trulicity shot had fast heart beat for 15 to 20 mins then it went away I will see what happens during this time in my system to see if I will continue Trulicity

started 3 months on .75 and a1c went up to 8.4 from 7.4 on rybelsus. next 3 months on 1.5 dose. daily numbers are no better. will ask doctor to go back to rybelsus. i was nauseous but at least it worked

I started Trulicity about a year ago. I’ve lost a significant amount of weight. The problem is the sever fatigue. It is awful. I stopped taking it, and within a week, I got most of my energy back. I also read that it can affect your thyroid. I have Hashimoto’s thyroid disease. It also can cause thyroid cancer. I have nodules, but they are stable. I’m wondering if it is connected somehow. I am so fatigued, I lay down 3-4 times a day, feeling like I can’t even lift my arms. I’m going to contact my doctor to see if I can take something else. I have insulin resistance, so I gain weight in my abdomen. I’d rather have that and exercise more. Anyone else having this problem? Read More Read Less

Wonderful experience so far. Been on Trulicity for about 6-7 years (I think - been a long time). A1C is very consistently 6.8-6.9. Lost a few pounds (20?) over the first two years, then plateaued (I had lost about 50 pounds on my own about a year before I started it). I had the diarrhea side effect off and on for a year or so (probably my second year). Took me a while to figure it out because it would hit 2-3 days after dose. Usually only lasted for an hour or so (one trip to the bathroom). Funny thing - doc upped the dose to 3.5 and the side effect went away. Makes no sense to me, but I am happy about it. I have had none of the muscle pain, etc. others have mentioned. I take it in conjunction with Jardiance, Toujeo, and metformin. I have had no side effects from them either. Read More Read Less

I was on lowest dose initially. Started feeling constipated & exhausted but didn't realize it was a Trulicity side affect. Had weight loss, but also was making better food choices and eating more meals. Major problem prior to med was I was only eating 1 meal a day. Dietitian gave me goal of 3 meals/day with 20-30 gms protein, each meal. It was hard for me but I wasn't helping metabolism with one meal a day. I've bern experiencing nausea and stomach pains, no matter what I eat. Totally exhausted, too. Still was not thinking it was due to Trulicuty. Was Increased to next dose. Next day while in p.t.'s waiting room, for neck issues, I started to experience severe shakes, lightheadedness, weakness in limbs and headache. I just didn't feel well. Again, did not connect it too thr med increase. Therapist monitored me, took b.p. & ckd vitals which were ok. Suggested I go downstàirs to see PCP, which I did. Vitals were ok, EKG was ok. Doc decided to order labs and a heart monitor, although cardiologist prior to all of this had done all kinds of tests due to a Dòc identifying AFIB at one visit. Heart is fine, since I never felt AFIB symptoms, I thought maybe the feeling I was experiencing in waiting room was AFIB. ??? I had all these symptoms the next day, too... shakiness, bad headache & weakness last night, 2nd day aftern dose & it dawned on me that I had just taken the new higher dose, the night before affects started. Anyway, now that it dawned on me that I increased the dose, maybe it is related to these episodes. Truly the symptoms made me feel awful. I texted my Doc in the portal about the very recent med increase, and I decided to search for side affects & found this site. To summarize, the symptoms I've had are extreme exhaustion, headaches, jitters, shakkness, weakness in limbs, lighthededness, firmer stools and just not feeling well. Feel next dose of this higher dose, will tell me a lot & I will attempt to update this review. PLEASE KEEP SHARING TO HELP OTHERS! THANKS TO OTHERS FOR YOUR REVIEWS. Although all of our bodies act differently, it's important to share so Docs know & don't ignore it as just a coincidence. As others have stated, WE KNOW OUR BODIES, THE BEST! Good luck to all.Read More Read Less

I have been taking Trulicity with no issues. Anything has to be better than Metformin for your stomach. In 4 weeks , I’ve lost 16 lbs with not changing much. I know longer think about food all the time or am hungry. Give it a few weeks to get in your system.

It's been 2 months my ac1 is down to 6.5 doctor believes once I'm on 3 mg a week ac1 should be in normal range. Down 20 lbs too. I'm so glad at 1.5 mg I have no side affects. I pay in 2 week when I go up dose I continue with no side affects.

The side effects over 6 month use were devastating. causing my health to deteriorate. Experts were not interested in my complaints and were hell bent on increasing dose. It failed to do what it was suggested, So stopped, much to the distain of the diabetic nurse. Offering yet another type with dreadful reviews.

I've only taken one dose and I have not seen any changes in my glucose levels. How long does it take to kick in?

I just stated trulicity yesterday and I didn't sleep well at all,my heart was beating fast,I will continue into next week but my legs are weak and I just don't feel like myself

"Decided to get off Jardiance and try Trulicity. Worst idea ever. My Apple Watch alerted me after a month that my heart rate has been more elevated than normal the past 2 weeks ( injection 3&4 of .75). Which I felt. The final straw was walking to pick my son up from school and getting in the car and feeling dizzy. I checked my heart rate and it was 145! It came back down but kept going back up doing simple stuff. I’m talking 161 HR Just going to do laundry. I finally called my Dr and told her to take me back to Jardiance. I went to the ER to get checked. Everything check out except my heart rate was elevated. And the only thing I’ve done or added different was the Trulicity. My last shot was last saturday and slowly my heart rate has returned to normal. I’ll take peeing like crazy with Jardiance over my super high heart rate with Trulicity."Read More Read Less

I have been on Trulicity for 15 months now. I have a love-hate relationship with it. Due to severe side-effects and the fact that I responded to it so quickly, my dosage was never increased. My A1c had suddenly jumped to 8.6 after being in the high 6-low 7 range with the help of Metformin and Tradjenta for couple of years. My A1c dropped quickly and my last one was 5.7. I have also lost 31 pounds which was much needed! That’s the love part. For me it works extremely well, even at the lowest dose. The hate part is the terrible side-effects. Apparently I am not “most people”. While they are not as intense as they were initially, they are definitely still an issue. I am keeping my fingers crossed. The past three weeks, though not without side-effects completely, have been the best I have had this far and hopefully the trend will continue! If so, my perseverance will have been paid off. Rather than switch to something which may have the same or even a worse effect and not been as effective, I made the decision to grab the beast by the horns and try to figure out and take note of what worked and what didn’t. For example, though it sounds counterproductive, keeping a little something in my stomach actually seems to help so for about three days I eat small meals supplemented with light snacks about every two hours. It is a love-hate relationship that has been going on for more than a year and finally it is showing some indication that finally it may be slowly improving.Read More Read Less

I just started Trulisty. About a few hours after my first injection I noticed I was getting a bad headache and nausea.Stomach also hurting. Praying this is just temporary.

Where to begin. Started Trulicity in October 2022. Started with some mild nausea and fullness. Fast forward to today. Dr pulled due to horrible body pain all over upper body, burps that where hard to pass, weakness, vision changes shakiness and not to mention severe headache that runs all over. I literally feel like I’m dying. I’ve never experienced anything like this. I’m hoping the side effects diminish fast. A week of this was enough for a lifetime. Be careful. Most of the severe side effects aren’t mentioned or discussed. Read More Read Less

My A1C was 8.6 and my doctor switched me to trulicity .The day after I took my first dose I started projectile vomiting ?? and I felt nauseous with the sour burps, chills, shaking, and a severe headache that persisted for 5 days afterwards. NOT an experience I ever want to have again!!! I was so dehydrated that I had to go to the Emergency Room. I was admitted to the hospital for 5 days. No prior g.i. issues before taking it. No second dose for me. Went back to Januvia and been on that ever since. Read More Read Less

Started on Trulicity.75 for two months. Some fatigue and mood changes. A1C dropped from 7..6 to 6.3. After 8 weeks the dreaded diarrhea and stomach pain began. I thought it was a bug but it continued. Doctor upped the dose to 1.5 and the nightmare continued. Now at 4 months and it’s horrible. Doctor suggested going every 10 days between injections. Days 1 and 2 are ok. Day 3-5 are horrible and then repeat. I have had enough and cannot handle the stomach pain And diarrhea as well as fatigue. I’m done with Trulicity. Read More Read Less

Started with 1.5mg. Side effects rough for 3 weeks. After 3 months it was increased to 3mg. Side effects are horrible. N/V, diarrhea, belching. Told my doctor no more.