User Reviews for Byetta (exenatide)

I took this for the treatment of Diabetes Type 2 management and for obesity, and it made me really sick to my stomach at first but did very well at controlling my appetite!

I have been taking this for 3 months. While I was on 5mg 2x daily, it didn't affect my blood sugar, but I did feel like I ate less food. Dr. changed to 10 mg 2xdaily, and now I feel ill and tired all the time, with dizziness in the mornings. I am not as pleased with the treatment as the best treatment for diabetes.

Getting the nausea feeling is ruff.feeling somewhat larthargic,small loss of weightblood sugar around 120-140 w metformin will discuss options with doctor

I started on Byetta 3wks ago and with 5mg. and have noticed a drop in bs and the nausea went away, but I'm noticing a slight swelling of my hands and face, also some headaches have been occuring. Anybody else experience any of these symptoms? I really like how this medicine has lowered my bs when nothing else seemed to work and would hate having to get off of it.

it worked really well in the beginning then i got really sick for a month and it hasnt worked since

What a great drug! I had a predisposition for weight-related Type 2 diabetes. In 1987 i started gaining 20 pounds per month so went to doc who checked my thyroid function and then misread it (always get copies of your bloodwork!!), telling me it was normal. Over the next 7 years I gained about 140 pounds and Type 2 diabetes along with Restless Leg Syndrome. After getting my thyroid under control, I started on other meds such as Avandia, which nearly killed me via fluid retention in chest/heart cavities. In the end I was on Metformin (2000 mg daily) and glipizide (5 mg). When these weren't enough, my endocrinologist gave me a choice of insulin or byetta. I chose the byetta and am I glad I did! Have been on it since Nov. '07 and have lost over 45 pounds. Since all this weight loss and blood sugars staying normal, I have been having low blood sugar episodes down in the 40's and 50's. Solid food will not bring it back up quickly because of the slowed digestion process, so must resort to sugar drinks or apple juice. The low blood sugar episodes happen fairly quickly after an injection. It may be time to cut back on other diabetes meds. Endocrinologist fully expects the diabetes and borderline high blood pressure to disappear with enough weight loss. I had some light nausea when first starting, but it went away quickly. Docs advise eating only when hungry and have lost the weight w/o even trying. It does make you feel bloated after eating due to the slowed digestion and feeling fuller longer, but this is acceptable for the benefits achieved. My HbA1c has dropped from 8 to 6.1 in feb.'s check. I have no injection pain due to a numb spot on my stomach from a tubal ligation, just some redness and occassionally a minor skin tear from the very fine needle and not holding it completely still. I do agree with a previous reviewer...every pen seems to be different. One pen was so hard to push I got a lot of skin tears. I love this stuff and can't say enough good things about it!!!Read More Read Less

Have been on this drug for 14 months and have lost 40lbs. My Alc is now 5.9. Still haven't been able to eat some foods as they make me sick just by smell and taste. Still get slightly nauseated every evening almost, but I am very pleased with this drug. Had to buy new clothes.

Started with A1C of 7.5,after 9 months am down to 4.8. I also started at 425 lbs and am now at 372. 53 lbs lost in 9 months so I can't complain. Some nausea after injecting but I found when I ate slower and smaller amounts that I didn't have the sick feeling as much. For me, the nausea, vomiting, etc. was really about how healthy I was eating while taking Byetta. In my opinion, you CAN NOT take Byetta and continue to eat like you did before--when you do, that's when you get the side effects.

.Lost 45 lbs. blood sugar more stable. the one problem that does bother me is the sometimes severe nausea and vomiting.

Although my sugars are great and the fatigue I experienced with Actos is gone, I am totally constipated! After taking the 5 mg for two weeks, I just stopped going. (Before that, I was fine; a cup of coffee could get me going.) Now, after Exlax, MOM, a Fleets 3 kit and a trip 4 days ago to the ER where they tried a saline lax, molasses enema and a Rx for Miralax, I'm still waiting and feeling scared. My doc says stay on the Byetta, but I am afraid every shot is just bringing me closer to my colon rupturing. What now? Read More Read Less

I just started 10 mgs of it. seems to be doing its job but not seeing the number yet. little higher than before. has cut down on my appetite though. haven't really felt too sick to my stomach, slight acid reflux. hope it will do it thing for me.

I love the results from the use of Byetta. I have used it for over 12 months. My A1C and blood sugar control has been amazing. The ability to help reduce my appetite is an added bonus. I would highly recommend Byetta. My only caution is that the first day on a new pen may cause some minor stomach irritation. Not worth stopping use of this miracle drug. I am wondering about any long term side effects.

I've been on the meds for 4 days . . . the nausea is becoming less, I'm eating less and not feeling hungry. My blood sugar has dropped, but not quite enough yet. I look forward to better results as time goes on.

DX with Type 2 diabetes. On Byetta for 16 month. Just got off it due to low blood sugar readings as low as 47. I work out at the gym 7 days a week and think my sugars are normal at this point due to exercise and diet. Liked what Byetta did for me but low blood sugar readings were a bit to much for me. Can't live that way afraid to go out or drive. Talked with my Doctor and was taken off it due to low blood sugar readings. Be aware of being tired and check your blood sugar when you feel like that it could be dangerous.Read More Read Less

I have only used this product for a couple of weeks have not experienes nausea, but the firs couple of days was constantly thirsty and experienced diarea,and a little blurred vision has improved the sugar level greatly dropped from high 400's to 130-170 range have a follow up appt. on the 23rd of April. overall I am satisfied with this product and will continue to use it...

In 11 months, I have lost 22 pounds. I always thought I was neuasous when I took Byetta, but I think it was just that I was no longer hungry! Then my creatinine went up and my DR. thought it was time for me to go on Insulin. In 10 days, I gained 6 pounds. Boy, Do I miss my Byetta now!!!

Nausea was absolutely horrific for the first 3-4 months. Then it disappeared, and now, I feel great. BS control is good. Before meals, 90-110 and 2 hours or so afterwards, 120-150. I am worried about tingling in my hands. Could this be the onset of dm induced neurapathy, even tho my numbers have so improved? I have lost 16 lbs and have about 25-30 to go.

After almost three years of usage I am starting to have trouble with the actual "pen" usage. The knob at the end does not want to turn and have had to resort to using a pair of pliers to turn it. The pharmist is of no help and when I called the company they tried to make out that I was a dummy and didn't know what I was doing. I also think that the drug's effectiveness has started to wear off also from long time usage.

I cant remember any drug making me sicker. I have tried 5 times to take this and evertime I get so weak and lethargic and it does not help with bg, wt loss, or anything. The Dr. said it is made from lizard spit? Maybe I am allergic to it. The drug co. is not honest with true side effects either. I would not reccoment this to anyone with gastroparesia either. Just awful.