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13 People found this comment helpful

Methotrexate has worked very well for my RA since starting it over 2 years ago. I recently started taking injections at the highest dose (1ml). To make the shots easier, I ask for allergy syringes as they are the smallest and work just fine. I've experienced a lot of hair loss/thinning and find that taking Biotin, 1-2 pills/day (over the counter and cheap!)has really helped. Dry mouth is also a ...

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Anonymous | 55-64 | Female | On medication for 2 to less than 5 years | Patient
1/17/2017
Condition: Rheumatoid Arthritis
Overall rating 2.7
Effectiveness
Ease of Use
Satisfaction

I started the injection because the pills gave so much nausea and gut pain. The injection is no different so if you are thinking it will be it probably won't be.

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Katherine27 | 65-74 | On medication for 6 months to less than 1 year | Patient
6/14/2016
Condition: Rheumatoid Arthritis
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I have been on methotrexate injections for over 6 months now. I have not felt any relief from joint pain and swelling. Side effects are my hair is falling out by the fistfuls and doctor prescribed Folic acid and I'm on biotin, but it's not helping. I also developed thrush in the mouth and have bad episodes of itching all over. I'm going to talk to my doctor about an alternative to this drug.

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HaleyJ | 45-54 | Female | On medication for 2 to less than 5 years | Patient
5/15/2013
Condition: Other
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I have been taking this drug .1 cc's for about 3 years now for my iritis. Is anyone else out there using it for this condition? It has been very effective with no side effects, allowing my doctor to wean me completely off the predisolone drops in my eye. My uncle who has RA also uses this drug and was told that because he is doing the injection as opposed to the pills, it is first absorbed in the blood stream as opposed to the liver and therefore he can still consume alcohol on occasions. Has anyone else ever heard of this? I would love to go back to enjoying a few glasses of wine here and there. Thanks!Read More Read Less

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Anonymous | 55-64 | Female | On medication for less than 1 month | Patient
11/26/2012
Condition: Psoriasis associated with Arthritis
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

have been ill every since starting the injections, can't keep any food in me, severe headaches, extremely tired. Throwing up.

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Anonymous | 65-74 | Female | On medication for 1 to 6 months | Patient
9/27/2012
Condition: Systemic Lupus Erythematosus
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction
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ladywebster | 55-64 | Female | On medication for 1 to less than 2 years | Patient
8/30/2012
Condition: Rheumatoid Arthritis
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction
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my love is in heaven... | 25-34 | Female | On medication for less than 1 month | Patient
9/1/2010
Condition: Pregnancy Located Outside of Womb; Often in Fallopian Tube
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I had gotten the inj in my back side, awful side effect's, I complained to my Dr. she said it was normal 21days later I was rushed to the ER, for emegancey sugery because my tube burst and I was bleeding internaley, I lost my laet tube. this was the worst thing that could have happen.

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leegleze | 55-64 | Female | On medication for 10 years or more | Patient
7/22/2010
Condition: Rheumatoid Arthritis
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I started on MTX oral immediately upon diagnosis of RA in 1990. Due to stomach "bleeds", my doctor put me on the injectable 3 years later. I took it for the following 12 years. Side effects I experienced were dry mouth, mouth sores, itchy rash, dry eyes and some lung problems. The doctor prescribed Folic Acid 5mg per day to clear up the mouth sores. It worked well. I put up with the other side effects because they were the lesser of two evils, the other being RA flares. Because I was on it so long, the doctor took me off it, without a replacement, and I was okay for a while, but just recently (2010), I had the worst flare of my life! Maybe it's time to return to MTX. I use acetametiphen with codeine if I feel a lot of pain because it doesn't bother my stomach as much as NSAIDs. However, I always have to take them with a stool softener because they can be very constipating. I also have Fibromyalgia & CFS, and have tried Lyrica and Neurontin for those symptoms. The side effects were horrendous from both ... I was a zombie and couldn't function. My family begged me to get off them because they were affecting our relationships. I also experienced short term emory loss while on these drugs, a function I've not been able to recoup. Read More Read Less

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Anonymous | 45-54 | Female | On medication for 1 to 6 months | Patient
5/8/2010
Condition: Rheumatoid Arthritis
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction
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Wanda | 55-64 | Female | On medication for 1 to 6 months | Patient
8/17/2009
Condition: Rheumatoid Arthritis
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I used oral MTX for 2 months than switched over to inj.(10cc) for 1 month-today my Dr. told me not to use it for 3 weeks because I had unusally high numbers on my liver panel. I also get severe headaches and vomiting. My Dr. assured me I would not lose my hair but it has gotten very thin.

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pookie1 | 45-54 | On medication for 5 to less than 10 years | Patient
8/8/2009
Condition: Rheumatoid Arthritis
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

the injections have fewer side effects for me than the pills. i am now able to take the maximum dose with no nausea or mouth sores. i take Imuran twice a day along with the weekly shots. doing much better than even when on Embrel. saving $$ too!

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Monielove | 25-34 | Female | On medication for less than 1 month | Patient
6/23/2009
Condition: Pregnancy Located Outside of Womb; Often in Fallopian Tube
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Im 27 and had an egtopic pregnancy and never hear of some one getting an inj, I had very bad side effects such as the sleepyness, and mood/mental changes I'm a manic depressent have been my whole life and never had a brake dow like this I was never given a side effect sheet nor an other option... Im no lab rat...

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Anonymous | 19-24 | Female | On medication for 2 to less than 5 years | Patient
6/5/2009
Condition: Rheumatoid Arthritis
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I was diagnosed with Juvenile Rheumatoid Arthritis when I was fourteen. My doctor prescribed methotrexate, and I had been taking the full dosage for about two years when my doctor halved my dosage. I had been doing really great until recently. I have been having flare-ups more frequently, and my new doctor (I had to switch when I turned eighteen) increased my dosage. She wanted to increase to a full dosage again but my liver isn't doing well so I am stuck at a little above half. I am still having more frequent flare-ups and have talked with my doctor about taking methotrexate with other drugs like Humira or Embrel. As far as symptoms go - I have had painful mouth sores, but taking folic acid had eliminated them. Every time I take methotrexate, I get extremely nauseous and am usually out for the rest of the day. Despite the symptoms, it had been a reliable drug up until recently, unfortunately.Read More Read Less

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Anonymous | 35-44 | Female | On medication for 5 to less than 10 years | Patient
4/13/2009
Condition: Rheumatoid Arthritis
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
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[email protected] | 25-34 | Female | On medication for less than 1 month | Patient
4/1/2009
Condition: Pregnancy Located Outside of Womb; Often in Fallopian Tube
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I had a methotrexate injection in my hiney, painful but went away quickly. It brought serious stomach pains especially when you had a bowel movement. My hcg never went up and it took over a month to get below ten. I was administered the shot when my hcg was at 6500, the doctors did not believe it would work and that i would need surgery. Iknow my bod and how well it takes to medicine, and how long it takes to recover from surgery, having a son already. Iwent wtih the shot and dont regret it. it was definetly the more painful way to go but i still have both my tubes. I am nervos of the side effects, since the shot i have lost almost all sense of smell, dont see this in the reading material as being a side effect but figured it was good info to put out there! i also have bad indigestion that has kept up now 3 months after the shot. interested in other side effects ladies may have, please make comments if you have had methotrexate for a ectopic pregnancy.Read More Read Less

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hope_62301 | 19-24 | Female | On medication for less than 1 month | Patient
3/28/2009
Condition: Pregnancy Located Outside of Womb; Often in Fallopian Tube
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

i had a shot of methotrexate for my second tubular pregnancy, it was that or wait to be scoped again. i am satisfied with it due to the fact i got to keep my only tube,but i don't really understand what it really does to that tube.i am unsure of the future, if i can still have kids or not, but i thank GOD for good health insurance that helps cover invitro!

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Anonymous | 45-54 | Female | On medication for 1 to 6 months | Patient
3/9/2009
Condition: Rheumatoid Arthritis
Overall rating 2.3
Effectiveness
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Satisfaction
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Seeking RA Cure | 45-54 | Female | On medication for 5 to less than 10 years | Patient
1/25/2009
Condition: Rheumatoid Arthritis
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I have had RA for twenty years and have used Methotrexate for about ten years, both the pills and the injection. The pill did not agree with me, made me sick and my liver was taking a beating. My doctor switched me over to the injection about 8/9 years ago and I have made major improvement since; however this is with the combination of REMICADE and not by it self. As a result of the RA and the medication I have also developed Sjogren syndrome, which I take Evoxac for. The Methotrexate has contributed to my hair lose, dosage varies from .4cc to .6cc. When I go up to .5/.6 cc my skin starts to breakout in white blotches and itchy pimple like bumps, that when I scratch the skin comes off. Although my Doctor tells me that I am in remission because I have not had any major flare ups, I tend to differ. I say this because I am suppose to last six weeks pain free (since this is how often I take REMICADE) but by the second week I start hurting and have to start taking over the counter NSAIDS, by the third week I have to start taking Prednisone and needless to say but by this time, I also look forward and can’t hardly wait for my treatment and two weeks of complete pain free. In addition, I watch what I eat, practice yoga 2/3 times a week (even when I am hurting, it seems to help) and seat in the hot tub. I guess ultimately, the Methotrexate works but only to certain extend; however I do wish I could stop taking it.Read More Read Less

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Anonymous | 35-44 | Female | On medication for 6 months to less than 1 year | Patient
11/26/2008
Condition: Rheumatoid Arthritis
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

This is my second time on Methotrexate. We finally went back to it after trying Remicade, Humiara, Enbrel among other injectables. They worked for a while but stopped. This med is much easier to use than the pill form which made me violently ill. My arthritis has tamed down and I have not had a flare since taking methotrexate. I have expierenced some strange hair loss that has not grown back even between treatment. I do spend most of the day in bed after my injection. Nausea meds help but I am very tired from the med. I also take folic acid with my injection. If I had to do it over again I would have stuck with methotrexate rather than try all the other injectables.Read More Read Less

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LadyA | 19-24 | Female | On medication for less than 1 month | Patient
11/22/2008
Condition: Pregnancy Located Outside of Womb; Often in Fallopian Tube
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I had a methotrexate injection to terminate a pregnancy in my tubes. The only thing bad I have to say is that I don't feel that the doctors fully explained to me what may happen after the treatment. I had no idea how long it would be in my system. They just said for a while which resulted in me becoming pregnant again and having the pregnancy terminated by the medication that was still in my system.

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