treatments with this type of drug, is not like what you are thinking. sorry, but, severe illinesses, such as b.c. crohnes, severe erlos danlos sydrome, pancreatites, birth defects, joint dislocations, renal tubular acidioses, brain tumor, in which cases i have had a lot more illinesses then i'm writing, i say, demoral can be hard on taking it for your severe pains. certain drugs, i too can't take, or my kidneys will shut down. but, this drug is highly, addictive, and the pills don't work the same as does a shot of a small dosage. i can't take morphine, nor simple over the counter drugs, it would just shut down my kidneys. i can almost say, i'm at my last shot? before another thing happens. be careful, its highly, addictive, and in my case, i don't have an addictive personality. i never drank in my life, nor use street drugs, not willing to get involved into medical marijauna to stopping my severe pain.i take a very small amount of this pain med, but, i wish, i could get another answere? i no longer can have tylonol its hard on my kidneys, not to mention, my liver. i'm ok. there tho. i think to each there own, as, whats best 4 the patient.Read More Read Less