User Reviews for carbidopa-levodopa oral

Currently, I m taking azathioprine 50mg, Pradaxa110mgx 2 times, 1 herbesser 200, prednisolone5mg at alternate days Caltrate, vit d, atorvastatin, vit b12, folic acid, Cozaar if I need to top up. Plus madopar 250mg but took only half the tablet 125mg with apo-levocarb125mg & comtan200mg…. 6-7 times a day. ??

I have SLE & asthma my SLE makes me very tired. Doc beleives that I may have msa- c., similar to parkinson therefore Im taking levocard 125mg 6-7times per day with comtan to prolong the levodopa & carbidopa.& I also take mardopar 250mg. But only half tablet together with levocarb & comtan. That means I m taking 125mg mardopar& 125mg levocarb & I tablet of comtan 200mg X 6 to 7 times depends on the situation. I will do a 2nd mri scan by my referral doc in a gov hospital in January 2025 to see if she can change my medication or not. ?? The tremors are bothering me as I have frequent falls & lost focus on my work & tasks that I used to enjoy. My dogs kept me going. ??Read More Read Less

I was diagnosed with Parkinson’s disease over 7 years ago and I was prescribed carbidopa/levodopa from the beginning the doctors kept increasing the medicine as my symptoms became worse over the years. After four years taking the medicine, I begin to experience frequent off times, when the medicine would stop working too soon or when it would take the medicine too long to start working. This increased until it was happening 3-4 times every day. My symptoms became worse and more out of control. I also began to have more episodes of brain fog. (I also have Thyroid disease, and had been diagnosed with having Graves’ disease, TED, and had also been treated for seizures several years prior to my PD diagnoses.) My vision blurred and I was seeing double and triple with multiple halos. Driving at night was impossible, and driving during the day was becoming more dangerous with the increased brain fog lack of activity. I was calling it my brain disconnect because it felt like my brain was not communicating with the rest of my body. If I was driving, and the light turned red, I needed to stop the car. My brain would tell my leg to slam on the brakes and stop the car, but my body wasn’t moving at the same speed as my brain was telling me to move. My body was in slow motion, and by the time the car had actually stopped, it was in the middle of the intersection, this was a big problem and I started to worry what would happen if a little kid happened to jump into the intersection and I couldn’t stop in time because of the brain fog. Even simple things like signing your name on a document, is difficult to do when your brain isn’t on the same wavelength. I have signed my name a thousand times over the years, but I couldn’t get my hand to pick up the pen and write my name on the paper. I just couldn’t do it! I had to quit working and I filled for disability. Then my VA doctors completely changed my treatment. I had been taking Carbidopa/levodopa100 2 pills, 6 times a day. My VA neurologist changed the Carbidopa/levodopa to 200 MG SA tabs ( I take 1 tab, 6 times a day) and he added Entacapone 200 MG (also 1 tab, 6 times a day). This has made a huge difference! Before, I rarely had an entire day without any major Parkinson’s problems or symptoms. Now I have between 1 and 1 1/2 days good days every week. A good day is when the medicine is working as it is supposed to, I am not having very many troublesome symptoms, I’m able to do some light housework, actually cook dinner, and then usually sleep fairly well. There’s some symptoms and side effects that I consider normal, I have all the time, and I just deal with them: migraines, lightheaded, nausea, lack of appetite Then I have a day of insanity! I don’t know what causes it but the day usually starts out with me feeling exceptionally well. The medicine seems like it’s working, and I’m feeling very motivated to get things done. I’ll eat breakfast, and begin doing whatever is running around in my head. Pretty soon, it feels like I’ve been triple juiced with caffeine and my mind won’t shut down until this “thing” is done. I start stumbling around and into walls, furniture, etc, like I’m intoxicated. I feel like I’m going to either pass out or throw up, and I go to lay down in bed. But I can’t stay in bed long and I’m back at it again. My heart feels like it’s beating faster than usual, but this insane day won’t end until it feels like someone has tripped the power breaker off! It feels like I’ve crashed or hit a wall. It definitely feels like my medicine isn’t working. I’m able to go to bed and get some sleep. The remainder of the day is spent in bed, taking my medicine when I’m awake and recovering. The next day or two after the day of insanity are usually bad days both physically and mentally. I’m exhausted and I don’t feel very good at all. My medicine seems to be working, but I’m very stiff, in a lot of pain, very bad migraines, my brain is fried. I have no appetite and no energy. After I beRead More Read Less

I have been taking carbidopa-levodopa for about three weeks. It has controlled tremors to almost nothing. But It has been the hardest drug to adjust to. I am almost always experiencing gastric reflux, sleep disruption, stomach pain, and tiredness although I take medications to decrease indigestion lessen sleep disruptions, etc. My only priority is exercise and I exhaust myself with most 45-minute doses of yoga and water aerobics. I am always tired and sleepy.

I was diagnosed with Parkinson’s in 2021. In the beginning, the medicine helped I could move around more freely. It stopped the tremors somewhat, and stop the bladder leaking.. But then it caused confusion and I was not able to drive anymore. The road looked distorted. The lines in the road looked wavy, but I have to take the medicine otherwise I can’t move so I guess it’s a trade-off until they come up with something better.

The off time is very painful for me, my whole body hurts multiple times a day,

I take a 25/100 AND a 50/209ER 6 times per day. I experience off time 4 hours after dose is taken. I also have a DBS

I have a love/hate with this med. I am 25/100 2 pills 4 times a day. It has made me functional. Prior to starting I was about to lose my hi-tech developer job. I could not type and could not think straight. I was walking with a cane and barely mobile at all. My left side strength was horrible. I could barely move my left arm. Forget asking the left hand to do much of anything. My wife and I nicknamed the left hand "Hook" because that was all it was good for. 2 months on C/L and almost all of the symptoms are gone. That is the good news. The bad news...insomnia, urge to pee all night (every hour), constipation, and a head-bob like Stevie Wonder when he is really into playing the keyboard and singing. I do my part with diet and drink. I have cut out sodas all together. My wife and I are very dilligent about following the Parkinson's diet recommendations. As an added bonus, C/L messes with my blood pressure. I never know when it will bottom out on me and cause me to have to sit or lay down when it happens. I bring this up to my neurologist and the reply is always to increase the dose, which in turn amplifies all the other side effect. I would love to give a lot more effort to the exercise part. It is kind of hard to do so when I go for a nice walk and end up having to lay down on the sidewalk due to BP drop. Same with stores. I try to go to Sam's just to walk around and get good exercise. I am sure they appreciate it when my lights go out and I have to lay in the middle of a grocery aisle to get my bearings. There really has to be a better way. It is a coin flip for me. I know what happens if I wean off the C/L, but if this is how I have to spend the next 15 years I would much rather check into hospice now and call it a day. I have had a very good life with a lot of travel and experiences most people don't get to do or want to do. Another patient I ran into advised me to make a "bucket list" as motivation. I tried and realized that I have checked off a lot of things already. In case you can't tell, another bonus is that C/L makes me ramble...lolRead More Read Less

I have been battling this damn PD for 15 years and it sucks! I have using this same drug and it is as bad today as it was 15 years ago. You mean to tell me this is the best the drug companies can offer? What a JOKE!

I've been on 25/100 three times a day a pill and a half each dose. Been on this for a month or so. Does anyone know what the relationship to meals is? Does it matter if I take the medication before eating? How long before? Or is it better to take the medication after eating, and if so how long after eating? Thank you, TBS

I have Essential Tremor that has affected almost every aspect of my life from bathing, dressing, eating, driving, talking, writing and walking. I have run the gamut of usual meds for ET and my Doctor tried carb-levo. It was horrible - nausea, water retention, sleepiness, severe dizziness and nothing positive. I was so disappointed again. I need something to help me just get through the day a little easier. I wish this had worked for me.

At first it seemed to help but going into the third week I was extremely nauseous, dizzy and couldnâ??t think straight! My tremors never went away. I had to slowly go off the medication because of all the bad side effects. I had wicked eye pain and had difficulty walking. There has to be something better out there than this wicked medication!

I am exhausted all of the time and am shaky much of the time. Also my walking is not good and I use a walker all the time. I am frustrated and have lost interest in many of the things I did before.

I started using Carbidopa-Levodopa ER 25/100 - 3 a day without side effects but also no symptom relief. Dr increased dosage to 50/200 - 2 a day which caused severe nausea all day without any relief of symptoms so I figured I hate the way it makes me feel and isnâ??t helping with symptoms so I stopped taking it. My general physician recommended a different neurological physician who prescribed NeuPro patches, started at 2 mg and increased the dosage to 3 mg and then to 4 mg which I still use. Then I decided to try carbidopa-levodopa again, I started with 25/100 2 times a day and my tremors lessened without noticeable side effects so I switched to 50/200 2 times a day and tremors stopped completely for about a month then they returned to my left hand. The Dr just upped the dosage to 3 a day but havenâ??t noticed much if any change but still do not have side effects that are caused by the Cardidopa-Levodopa. Read More Read Less

I started using Carbidopa-Levodopa ER 25/100 - 3 a day without side effects but also no symptom relief. Dr increased dosage to 50/200 - 2 a day which caused severe nausea all day without any relief of symptoms so I figured I hate the way it makes me feel and isnâ??t helping with symptoms so I stopped taking it. My general physician recommended a different neurological physician who prescribed NeuPro patches, started at 2 mg and increased the dosage to 3 mg and then to 4 mg which I still use. Then I decided to try carbidopa-levodopa again, I started with 25/100 2 times a day and my tremors lessened without noticeable side effects so I switched to 50/200 2 times a day and tremors stopped completely for about a month then they returned to my left hand. The Dr just upped the dosage to 3 a day but havenâ??t noticed much if any change but still do not have side effects that are caused by the Cardidopa-Levodopa. Read More Read Less

I have restless leg syndrome. I recently increased my dose of er at night and got the first nights sleep in a long time

Increasing my med (carbo ) from 3 times per day to 4 times per day made a big difference.

I can only take a half pill at a time or I am extremely dizzy and it puts me to sleep. I am taking this for restless leg syndrome. I also have bulging discs and this medicine helps with the pain and discomfort from that as well.

It literally has given me back my life. I have freedom of movement, more energy and no brain fogginess. I occasionally have a problem with the first dose of the day, I may have severe nausea, but I've learned to eat a cracker and have a sip of water. In the beginning I felt like a pulling sensation in my neck, but that has disappeared. I currently experience a nervous twitch, I constantly want to move my foot or my body. I can control it, once it starts, I take a deep breath and relax my body. It's been 2 months since I started taking the medicine. I'm up to the full dose. I'm hoping the nervous twitch eventually stops. I see my neurologist next month to review my progress and if at that time, I'm still experiencing the nervous twitch, I'll bring it to his attention. This medicine has made all the difference for me. Two months ago I could barely type, today I'm typing this with no problem. I'm hoping this medicine will continue to work for a long time, until at least a cure can be found. Read More Read Less

Prescribed for RLS, has made an increase in my shakiness, causing me to loose balance more often. No stomach or actual brain effects. No ease of RLS symptoms.