User Reviews for Rexulti oral

I was on this medication for several months and it was ok at first but then it made my anxiety way worse then it was before I started taking it … I would have days where I couldn’t even get out of bed …. After a while I stopped taking it and I had body shakes and trouble sleeping and lost my appetite….. I have been off of it for about 2 months now and I’m still trying to shake the side effects away

I was on Wellbutrin for MDD since 2018. I was doing well just on this medication, but eventually I experienced persistent sadness/low mood, crying spells, anhedonia, lack of motivation, poor concentration, racing thoughts, anxiety, insomnia, and mood swings during my period. I was functional to an extent, but felt like I was barely getting by at work. I had mental blocks, was falling behind on paperwork, and felt stressed. I wanted to quit my job so many times. I needed an adjunct to my anti-depressant. I already tried Lamictal but got the rash, and Abilify but felt like a robot. Then my Dr. put me on Rexulti in January 2022. I was initially strongly resistant to the idea of antipsychotics, but gave it a chance. For the first few months, my mind was like a blank slate. It was strangely calm. Med helped to organize my thoughts, think more clearly, and stabilize my mood. No more depressive episodes or crying spells. No anxiety. Motivation returned. I still struggled to have energy, especially waking up in the AM, but I felt so much better. I became cognitively sharper and able to complete my work more efficiently. I felt very emotionally stable and was able to travel and enjoy my life! My appetite increased and I did gain like 10 lbs during the 1st year, but I was able to maintain the same weight for most of the time. That is until March 2023. Weight gain creeping up. I gained another 10 lbs. July to December 2023 another 20 lbs. Then December 2023 to now? Another 20! More than 50 lbs. It alarmed me. Clothes no longer fit me and it upset me. I had my annual physical in November 2023 which showed high cholesterol and I was this close to becoming pre diabetic. Diabetes runs in my family. My mental health’s never been better but at what cost? My physical health? For this reason, I’m choosing to get off Rexulti. If it wasn’t for the weight gain, I’d stay on Rexulti. Read More Read Less

I take this medication for Bipolar Disorder Unspecified & BPD. Honestly there was a little while where I thought I was better off not taking it, but after a week of not taking it I had a manic episode and was sobbing uncontrollably. Taking this medication in the morning works best for me. I no longer think everyone hates me, I have energy during the day, and I'm able to look on the bright side of things. I have been through probably 20 medications to help me and this definitely suits me the best. I may have gained weight but my body image is significantly better and I feel like I'm a more pleasant person to be around. Would definitely recommend this medication! I only take 0.25mg because I'm sensitive to medications.Read More Read Less

I have only been on Rexulti for a week, I always read the side effects with new medication but failed to do so with this new medication. As I started to take my medication tonight I decided to read up on the medication. BINGO! Since starting the medication I’ve had breathing problems. With a history of Asthma, naturally I thought that’s what it was. I did not take the medication tonight and I will not be taking it in the future. Several other side effects that bother me because my doctor prescribed this new medication knowing that I have all these other health issues. Side effects can be serious! I haven’t had more than 2 -3 hours of sleep each night since starting the medication. If it helps other patients, that’s a plus. It’s not the medication I need!Read More Read Less

I didn’t believe the hype. The first week I was tired in the morning. Then boom this with my lexapro is magic. No dred and I have GAD hyper vigilance and it’s much better. It also made me stop smoking. I feel great. Dreams can be an issue at first but I had stopped my Prozacin. This truly saved my sanity

My husband was on this drug as an addition to his antidepressant. This drug has ruined our lives after he was only on it for 7 months. It is not an anti-depressant, but an anti-psychotic. We have been dealiing with the aftermath of this drug for 2 years now. Stay away!

If ypu have a condition that lowers your blood pressure already, Be careful. Im 41 and also deal with Pcos which lowers my blood pressure sometimes. Concerning the meds. It makes me dizzy, gives me a headache and my anxiety doesn't get any help from this med. I don't know why my Dr. wants me to stay on it. I can only imagine it is cause i have been taking abilify. I had a bad reaction due to a combo of my pcos and this med together. One day i woke up at 6 am, i got lightheaded, dizzy and i remember walking towards my bedroom and all of a sudden i couldn't hold myself up I fell to my knees for a few seconds and then went face forward. I busted my nose and couldn't get up for a few seconds and when i did there was a small puddle of blood on my floor. I have pcos, so i think a cyst on top of my overy ruptured causing my blood pressure to lower and these meds also lower your blood pressure. I went to the e.r and they ran tests. Be careful if you have any condition or other med that already lower your blood pressure. Keep visiting and consulting your primary dr along with the mental health dr cause rexulti can cause you to pass out and get injured being it lowers your blood pressure by more than other meds i have taken.Read More Read Less

READ FULL REVIEW: I had been on Lamictal for my OCD and Bipolar dosorder since I was 12. I continued to experience overwhelming thoughts and manic episodes for most of my life until the age of 25. I went to a hospital for SI and although I had two other meds for depression and ocd, I was at a loss because nothing was working. I realized in the hospital as well I had a severe eating disorder and was able to work through therapy to get to a better point, but I still just wasnt there yet. I had trouble taking my meds consistently and it was really effecting my mood swings. Because of this also my Lamictal gave me a rash and I thought I was back out trying all the meds that previously didn’t work. That was when my doctor recommended REXULTI. I have been on it most consistently than any other med for about 6 months. Here is why I love this med. 1: I LOVE TO EAT! I was severely malnourished and this med helped me with my lack of hunger cravings that was a result of years of suppressing hunger. This has helped me with my confidence and I can finally work out. 2: MANIA AND HYPOMANIA REGULATED This med works great for regulating my highs and lows, which I have never found my other meds to actually achieve. 3: DOOM IS GONE I hadnt cried in about two months which is my lifetime record. I just was able to handle my emotions better. 4: MISSING 1 DAY DOES NOT EFFECT ME. This one was huge. If I miss a dose I am less likely to fall into a mood swing or episode and therefore have been able to remember and take the following dose instead of missing it due to my illness symptoms. Keep in mind that I have copious amounts of therapy as well as two other meds for ocd and depression, with all that in mind, I love this medication.Read More Read Less

I was on Viibryd and this was added at 2 mg to help my depression. I started having trouble swallowing. So I went to GI Dr and had scope down throat. He basically found no issues. The depression was still bad so my dosage of Rexulti was upped to 4 mg about 2 weeks later I started experiencing numbness in my arms and legs, could barely swallow. I was at a friends on vacation. I had a few days left before I could fly home. In those few days I got to the point I couldn’t dress myself, could barely shower, was drooling, slurred speech, and could barely swallow. So I flew home went straight to ER and had lots of testing done and a neurologist walked in looked at my meds and said it’s the Rexulti. I had what they called Parkinson’s syndrome. I was in the hospital 3 days, had to have a friend stay with me and help me. I have to have speech, occupational, and physical therapy (at home) plus the Parkinson’s meds for about 4 months. I had to follow up with the neurologist for about 6 months. I ABSOLUTELY WOULD NOT RECOMMEND THIS MEDICATION TO ANYONE!!! I’ve suffered from depression and anxiety for 40 years and been on meds for years and never experienced anything like that nightmare. Pray that I never will again!!!!!!Read More Read Less

I use 1 mg of Rexulti (augmenting Zoloft) for pretty bad OCD--it works! I previously tried so many SSRIs--my OCD was resistant until adding in the Rexulti. Relatively few other side effects, but some lethargy and increased appetite at times. Small price to pay however. This medication is absolutely effective for me.

I started this medication to help with the depression as an addition to my bipolar and anxiety medications due to the decreased risk of worsening my akathisia which I have lived with for almost 5 years now. In the first two weeks of taking this medication I thought I was going insane. I couldn't think of words, and my short term memory was shot. I've been off the medication since June and my memory issues are getting worse. While at first I was misremembering things, now I have virtually no short term memory. I wouldn't recommend this medication to anyone. I'd take the akathisia over this misery. Four months later and my symptoms are still consistently getting worse.Read More Read Less

I was experiencing severe psychosis and massive panic attacks multiple times a day. This has helped me so much!

I immediately got anxiety and restlessness. I had to stop it cold turkey after about a week of taking it every other day. I was also taking BuSpar for the first time, so I don't know if that was what was making me anxious too or not but I stopped both. I'm just on Wellbutrin now and amitriptyline at night. I'm going to call my doctor and let him know how I feel. My depression is horrible right now. Would not recommend this.

Been on it 5 weeks. Definitely eased up my racing mind, BUT I can't stop eating.

Has helped to keep me flattened

I am grateful I found this medication! In only 2 days my depression and thoughts of not wanting to live was significantly decreased!!! The only negative effect so far in the 5 days taking it I think is feeling, ill, feverish, but this could be a possible virus so Will let my Dr know if it continues. But as I said it is a huge improvement in my depression!!!!

There has not been a medication that has truly worked well enough to treat my depression. Once on Rexulti, I was feeling so much better. I am also taking Lexapro with it. The two work very well for me and I would be lost without them! So grateful it has helped me.

Almost 40 yr old female dealing with severe ADHD, PTSD, anxiety, severe insomnia, and treatment resistant MDD. This medication did give me some mania (nothing like Homeland mania, just 15% more annoying), and my sleep is a bit whack but I'm getting more sleep than before. My first month, I just wanted to eat. I didn't feel hungry. I realized my depression was getting better and I now find laying in bed all day BORING. So, I turned to food. Month 2, I turned that boredom to working out. I'm now in month 3, eating regularly, still working out, intrusive thoughts still like to pop up once a day but it used to be unending. I'm also taking Wellbutrin, Ambien, Xanax, and Ritalin. Have not needed my Xanax for panic attacks! Wild. Take everyone's experiences with a grain of salt. We're all on different meds, difference ages, our brain chemistries are so different. Psychiatry is a trial and error game. Hope you find happiness and peace.Read More Read Less

After taking Rexulti for three weeks, I see a worsening with depressive symptoms, lethargy, increased appetite, and somnolence during the day. With its 96-hour half-life X 5.5, the drug should be totally out of my system in approximately 21 days. However, with my immediate discontinuation of the drug, I look forward to feeling better within the next few days.

Very dangerous drug! Worked reasonably well for the first 12 months or so but I got a delayed onset of augmentation and severe side effects including debilitating sexual dysfunction that is worse than some of those PSSD reports you read. Tried to taper over a few months and that also resulted in a extremely severe delayed withdrawal syndrome that landed me in the hospital 5 times over the next 12 months and I had to re-taper from a very low dose to 0.015mg over the next 18 months and still suffering debilitating withdrawal symptoms despite following a very slow and careful hyperbolic taper. I have been on disability support since and couldn’t work for the first 6 months into withdrawal. This drug is one that can have you physically dependent like some of the worst drugs out there. Consider this before you decide if it’s right for you, especially if it’s been offered for depression as there are many great non drug alternatives. Read More Read Less