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3.5 Overall Rating

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Ease of Use

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Most voted positive review

63 People found this comment helpful

I started this drug about 2 months ago after struggling with IBS with Constipation for most of my adult life. I am now 42! I finally found a gastro who heard the fact that I only had a movement about once every 7 days and was shocked and actually told me, that is horrible and not normal and lets try some things to change that. I got some samples of Linzess and began them after finishing up a cou...

Most voted negative review

18 People found this comment helpful

This drug caused a burning sensation in my esophagus, making it hard to swallow. Because of that, I had to have a barium swallow, which caused severe constipation for 3 months and a hospital bill of 3 hundred dollars that I have yet pay and is now destroying my credit. I feel I should be compensated for my loss and aggravation.

Shared reviews and ratings

Meg | 55-64 | Female | On medication for less than 1 month | Patient
10/25/2024
Condition: functional constipation
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I took this 30 minutes before any meal and had 4 sessions on the toilet spewing out acid-like, brown water that burned and left me sore. No hard stools in sight! This felt like bowel prep before a colonoscopy. I can't imagine taking this every day or travelling anywhere once it's taken!

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Elle | 65-74 | Female | On medication for 1 to 6 months | Patient
7/18/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I started Linzess because IBS-C was affected my ability to function and made me miserable. I’ve been on 72mg for three months, and my symptoms are nearly resolved — though I have a few bouts of pain and bloating. I take dicyclomine on those days. Not sure when it started, but back surgery three years ago made me horribly constipated from taking opioids for pain relief. Sounds like I got stuck in the same cycle of OTC drugs, fiber, etc, as many others. This drug is the first to give me daily relief with regular bowel movements and relief from bloating. It was worth a try — and it’s helping me live a more normal life.Read More Read Less

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Linzess | 65-74 | Female | On medication for less than 1 month | Patient
7/16/2024
Condition: functional constipation
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I was prescribed this for constipation (small hard pebbles). I took it only once because shortly after I took it I had a bowel movement, still pebbles, and then brown acid like water which burned terrible. I had to cancel work that day. Never again!!

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Linzess | 65-74 | Female | Patient
6/18/2024
Condition: Chronic Difficulty having a Bowel Movement
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I’ve been using it for 5 months

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Kenn | 75 or over | Male | On medication for 2 to less than 5 years | Patient
6/3/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

This medication is what I call..."Exlax on steroids"!!!!!! It worked but too well, that is I didn't have constipation any longer but the diarrhea, having to sit on the toilet for at least an hour, flipping a coin to see IF I dare leave the house, and the closeness of a toilet. I even went from 290 mcg down to 72, not much difference. I have to find something else.

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Bison69 | 65-74 | Male | On medication for 1 to 6 months | Patient
5/23/2024
Condition: Chronic Difficulty having a Bowel Movement
Overall rating 2.7
Effectiveness
Ease of Use
Satisfaction

When taking with 16oz of warm water every morning I experience bowel movement Dailey but most of time it's diarha with bloating throught out the day.Havent been able to adjust outcome

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Nana | 65-74 | Female | On medication for 1 to 6 months | Patient
5/18/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I was given a diagnosis of IBS-C...pretty much a I have no idea what your problem is so we'll just call it IBS-C!! REDICULOUS as I had not a single symptom however my GI doc at the time prescribed Linzess. Well I had no more relief then if I'd used Miralax and it's a $600 a month medication...seriously!!! I am now using Senna and pay only $4 a bottle!!

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Ady | 13-18 | Female | Patient
5/17/2024
Condition: Chronic Difficulty having a Bowel Movement
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

This is the first medicine to make me feel better. It worked amazing for the first two weeks but then I broke into hives and had severe diarrhea.

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Anonymous | 65-74 | Male | On medication for 6 months to less than 1 year | Patient
4/27/2024
Condition: functional constipation
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I have been a chronic opioid user (suboxone for recovery) for years. In the last 2-3 yrs. opioid related constipation has gotten bad ...eventually having intestinal surgery. Before & after surgery I was prescribed otc miralax. It helped somewhat but I had to pee 20 times a night. I quit the miralax and a Dr prescribed linzess 290 mgs. There was some initial diarrhea but only little first day or two. Since then (about 6 -8 months) it has worked pretty most of the time. I still have to watch my fiber etc. But here's the problem. I developed overactive bladder and have pee at night often every 20 minutes, ALL NIGHT LONG!! It has severely affected my quality of life. But I'm not sure if it's related to the linzess or not. Drs seem to think not. It's almost impossible to stop in order to see be I become immediately constipated. Has anyone experienced frequent urination from this medication?Read More Read Less

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Anonymous | Female | On medication for 1 to 6 months | Patient
4/26/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

The medication srop working after a month, then I increased it ti 2 pills and it started working again for a week then stop again. So, now I am trying another medication.

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Jessica | 35-44 | Female | On medication for less than 1 month | Patient
4/13/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I went to the hospital thinking I was having a gallbladder attack. I was in unbearable pain. Testing showed I had stool backed up to my small intestine. After a few days of getting out of the hospital I visited my family doctor. He put me on linzess. This medicine changed my quality of life for the better.

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Sumer | 45-54 | Female | On medication for 5 to less than 10 years | Patient
4/5/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I have IBS- and Linzess started working OK at first I was running to the bathroom because the diarrhea was real. Run Forest run.???????? this medication ain’t no damn joke. I had a lot of bloating, and still having constipation. My stomach had pain and I didn’t understand why and where it was coming from the Linzess stopped working so I finally made another doctor’s appointment. The doctor took my doses up to 290. I’m getting a CT Scan done on my stomach to make sure there aren’t any complications going on. In the meantime, I’m going to try the 290 dose and see how I do do …. Get it …do do ????????Read More Read Less

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ColoradoCrystal | 45-54 | Female | On medication for 1 to less than 2 years | Patient
3/30/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

This medication has saved me from a life sentence of chronic constipation and all of the side effects that occur with 30+ years of IBS-C. I knew my IBS-C was inconvenient but until recently I thought using the restroom twice a week was a lot and hadn't realized how miserable I really was and how many symptoms are caused by literally being full of $#_&! I had to have my doctor adjust my dosage a couple times to get the perfect dose and being a new medicine, my doctor wasn't an expert on how it would effect everyone individually but with a little patience and a few weeks staying close to the toilet I couldn't be happier with the outcome! If you truly have severe ibsc you will know that a few weeks of uncomfortableness is nothing for months and months and now years of being symptom free! I am no longer fatigued I feel lighter I act happier there's actually a bit of pep in my step now as I look forward to taking my days on! I'm sad that I missed feeling good and didn't realize that what I was experiencing wasn't normal aging. I didn't know how many symptoms I really had that were caused by ibsc that I just thought were normal and now realize that they are not normal and it is a wonderful feeling to be able to go to the bathroom every day. For those who are not affected at all to those who are getting diarrhea I'm telling you stick with it, have your doctor adjust your dose, drink plenty of water and you too can get permanent relief. As was explained to me with first prescription by both my doctor and my pharmacist, it's not a take one time miracle cure, it's a process and it's something that you have to stick with but if you're willing to stick some cramps and diarrhea or some constipation and bloating while you get your dosage right, it will pay off. I've been on this for several years now and I am ecstatic about this drug. It would be devastating to me if something were to happen to my prescription and I had to go back to living (if that's what you really want to call it) the way I was before. Maybe it's not for everybody but boy am I glad it works for me! The side effects only lasted about a week after I got the correct dosage and have been side effect free ever since.Read More Read Less

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Frustrated | 35-44 | Female | On medication for less than 1 month | Patient
3/20/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I've been taking Linzess for over 3 weeks and it has made my constipation worse. It was hard enough before, but now they are so much bigger I can't pass them at all. Same rock hard consistency. I'm so jealous of the people saying they got diarrhea in the first few days.

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Marie | 45-54 | Female | On medication for 1 to 6 months | Patient
3/9/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

So I have been taking Linzess for a couple months and it has definitely helped with my constipation, however, the bloating is terrible, my stomach just inflates since I have taken this and it makes me uncomfortable and feel fat. It does also cause some gas for me but the bloating is really making me change my mind on taking this even though it works great to help my IBS-C. I do get diarrhea but it stops within about 4 hours from taking Linzess.

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Monicag | 25-34 | Female | On medication for less than 1 month | Patient
1/28/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Linzess is a miracle for me and I’ve only been on it for a couple days. I was just diagnosed with ibs c after years of struggling I finally went to a gastro. For an entire year before linzess I tried stool softeners, probiotics, exercise, a high fiber diet, miralax, and nothing was working. Being on the med daily for only three days after years of constant nausea, bloating, and abdominal pain I finally got relief. I’m now regular and my family notices major improvement in my happiness as the gut and mind are connected. Only side effect I have is gas. Read More Read Less

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Searanger | 55-64 | Male | On medication for less than 1 month | Patient
1/27/2024
Condition: Irritable Bowel Syndrome with Constipation
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I have had gastritis since birth. But at 50 I was having chronic inflammatory constipation. I can no longer tell if I'm full or empty for all the damage to the lining and a neuropathy issue. Not a drug I will take every day but when I need it.

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Steve T | 75 or over | Male | On medication for 1 to 6 months | Patient
1/10/2024
Condition: Chronic Difficulty having a Bowel Movement
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Initially my GI physician prescribed 72mcg Linzess, which did absolutely nothing to reverse chronic constipation. He then increased strength to 290mcg. After about six weeks, constipation resolved. Over the last 30 days I have found skipping daily usage appears to work better for me. The day I take the pill I experience one episode of liquid fecal explosion. Remainder of bowl movements are normal for that day. Because Linzess is a tier 3 medicine I go through “hell” to get insurance to approve it. Can’t decide if my needs might be better served if my physician would issue a new script for 145mcg. Not sure I want to go through all the insurance (bull), or just continue taking the 290mcg every other day. Read More Read Less

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Jay88 | 35-44 | Female | On medication for less than 1 month | Patient
12/25/2023
Condition: Chronic Difficulty having a Bowel Movement
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

This is the worst medication I have ever taken the type of diarrhea you get while taking this medication is ridiculous to the point where you cannot hold it in it’s really bad stay away from this medication

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Garla Armstrong | 65-74 | Female | On medication for less than 1 month | Patient
12/14/2023
Condition: Chronic Difficulty having a Bowel Movement
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I thought I was gonna die. Server dehyration vomit headaches gas diarrhea etc. Been sick a week. Doctor started me at 299mg. Still can't eat or drink. My chest hurts high blood pressure. Bedridden. Going to hospital. It's real bad stuff. Drug makers need ti be sued

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