User Reviews for fluorouracil topical

Not much until day 8, now day 12, lots of red patches forehead and temples. Only doing 1x/day per Dr. instructions, I am in the midwest winter and retired so homelocked for 3 weeks until treatment over. Just starting to itch, know the "worst" is yet to come but thats the price of stupidity of 100s of rounds of gold in my 30s with no hat or sunblock, feel lucky to have precancerous (so far) issues only.

I have had to use this product 3 times. It is absolute HELL. I was in so much pain by the forth week of use. My entire chest was looking like raw hamburger. I couldn't even let my shirt touch my chest it was so painful. I have to drive for my job and I had to have one hand under my shirt to pull it up and keep it from touching my raw skin. I had to do this treatment 3 times. If it had worked the first time, that might not have been so bad, but 3 times was too many. I hope something better comes along. I will try Diclofenac gel the next time. 5 FU is mostly just...FU, this hurts.Read More Read Less

This definitely works! Although the 2 weeks on/ 2 weeks off/2 weeks on schedule was a little painful- and the the unsightly breakout appearance during the healing process was rough. BUT the great news is for me- new skin regenerated after 4 weeks...very smooth and lesion free! I definitely recommend using Aquaphor cream available at drug stores to help relieve the treated skin afterwards... product worked for me!

Never again use for facial treatment! Strongly recommend you ask your dermatologist for other options. I erased 8wks of my life going through application of cream to face, ears, and neck, followed by recovery only to recognize a small improvement. If you have a sedentary lifestyle, it may be OK (other than continuous sleepless nights). If you are an active, outdoors person, standby for "hell"...

There should be more of a warning on website and on tube for keeping this medication locked up. If a pet gets into this, it is deadly within hours.

Too many days at the public pool as a kid unprotected. Prescribed Flourourcil for four weeks to be applied to my face and ears. I’ve just completed week 2 of 4 and have all the burning, itching and he’ll described in other post. Advil and various alcohol beverages have helped so I will muscle thru to the end with hopes of healed facial skin. If successful, I will be golfing and fishing with a wide brim hat. I’ll post a follow up after week four.

To say that I hate this treatment would be a vast understatement. The pain, cracking, redness, scabbing, jolting jabs of pin-like piercing and continuous extreme discomfort can not be over emphasized. I’m on day 17 of 30 and I have no idea how I’m going to make it through this. Obviously nipping any cancer early is the goal but this is horrendous and I haven’t even gotten to the worst part yet. Hate hate hate this in the fullest sense of the word.

I’ve just completed 2 weeks of a 4 week regimen. My face is very red and burns with some itching. Vaseline has been a relief and soothes the burning. I haven’t experienced any blistering or peeling as of yet. I’m not particularly vain about my looks but glad to be able to wear a mask in public and not seem weird. I decline invitations to lunch because I feel my face would be grotesque for someone to look at while they try to eat! From now on, I’m wearing sun screen and a hat while outdoors! Lesson learned.Read More Read Less

Used first on temple 2x for 14 days, developed 1 red sore spot. Waited 2 weeks and started 2nd treatment on forehead, developed GI side effects (slight nausea & IBS symptoms after eating evening meals) during the second treatment week. Since this side effect did not appear during the first treatment I did not make a connection until I heard this was a chemo drug. Figured it was because I was using more medication the 2nd time to treat a larger area. My forehead looked like a bad case of the measles and painful to touch inflamed areas. Best description when touching was rubbing sand on a bad sunburn. Although annoying not anywhere near some of the other skin reactions described here. Takes about 3 - 4 weeks for the red spots to dry out, flake off and disappear. Better than freezing treatment over a large area.Read More Read Less

Well us Scottish lads have a lot of things to be thankful for but olive oil bronzed skin is not one of them. I have always been outdoors from a very early age...baseball, basketball, swimming, golf etc. Sunscreen wasn't a thing when I was younger. Fast forward...play golf 5 days a week and every year would go to dermatologist and get a spot frozen or cut off. After wining about more spots to be cut out, I asked for alternatives because I was tired of scars on this handsome face! Enter Fluorouracil. During the first 5 days, red spots formed on my temples and cheeks which were obvious before but my forehead and cheeks started lighting up as well and nothing was visible before. Yep, I covered everything. Prescribed 2x/day for 14 days. Days 10-14 were rough, skin bright red, tight and itchy. My Derm recommended no lotion until finished - I complied. Was prescribed Hydrocortisone cream for healing with my choice of moisturizer (vaseline). Guys and Gals this process takes commitment and it was tough. But it has worked UNBELIEVABLY! Skin is soft, red spots and dryness gone and new outlook on life. Sunscreen (SPF50) every 2 hours with a wide brimmed hat to cover the ears. Do it! If you're already doing it hang in there and finish...it was worth it.Read More Read Less

I hate this stuff , they need to put on the tube to watch out while taking a shower. Using it on scalp(and other places) it was about 10 hours since applying it and didn't think while in shower until I tasted a bitterness. Oh crap I looked up to get it to flow down my back. It was to late and when I got out my entire face was red and blotchy ; it only got worse from there. My face and forehead burned and peeled for 3 to 5 days from what I guess is the skin there is more tender. 2nd go around I was careful but still face looks like severe acne, don't know if I'm rubbing it and don't realize. I'm also applying a Calcipotrien cream on top of it , don't know if that is making it more potent. I can handle it in other places , from bloody oozing sores to burning like hell. I guess thats what I get for working in the Texas sun for 20 years and not protecting myself. Read More Read Less

Used the cream 2x a day for 2 weeks on my chest. My chest feels like it is on fire. Hrlps when i put a warm cloth on it. Wonder what i can use to ease the burning feeling?

The worst experience since almost dying in child birth. Painful painful burning painful.

1st go round was aldara on my lower lip and darn if that Dermo told me nothing of the side effects!! I was dying after 2 weeks of 3 week protocol. Blistered swollen bleeding .couldnt eat or drink except thru a tiny straw. Called him- NO return call! New Dermo now and doing flurou. 5% on chest- horrible looking!!

Applied to my lips for 5 days and yes, it is painful after the 3rd day of application but the end results are great. My lips took about 2 1/2 weeks to heal 100%. I was in pain for about 6 days and it’s difficult to eat, drink and brush your teeth. It’s a rough procedure but worth it.

Satisfaction is a tough one, because it is very painful but it definitely works. I'm on my third round of treating AKs on my chest, shoulders, back and arms. The first two weeks of a four week treatment are not too bad, the third and definitely the fourth suck. It's like being itchy and on fire at the same time, and the appearance is horrible. I just finished the fourth week and my skin looks hideous. I forgot about this little trick, but just remembered last night and wanted to share: diaper cream. I slathered it all over the red, scabby areas and it's like a miracle. My skin looks about 90% better today. It still feels a bit itchy and some scabby areas, but overall I don't feel I have to wear a turtleneck so as not to scare people.Read More Read Less

First, it definitely irritates healthy skin. Second, the scabbing, weeping and peeling continues for weeks after treatment is stopped. Doctors who don't warn patients of this are remiss. But the medication is cheap with insurance and has a good track record.

Doctor prescribed Fluorouracil to treat Actinic Keratosis. once daily for 14 days. It is working exactly as it should. Skin is red, itchy, dry and after 9 days it is very difficult to sleep. But best to tough it out and get it over. 5 years ago, Doctor prescribed Zyclara which has a two weeks on, two weeks off, two weeks on treatment schedule. That worked beautifully turning all pre-cancerous patches into scabs and then new skin. I do not recall the same itching, burning, dryness from the Zyclara treatment that I am experiencing with Fluorouracil, but I wanted to get treatment over sooner. If I have to be treated again, I think I'll go back to Zyclara.Read More Read Less

Wow I woke in the night with severe stomach pain headache feeling miserable like I’ve been poisoned

causes burning and itching sensation. I had to stop after one week.