I was "talked into" trying this medication for the pain associated with Osteoarthritis. I have had it for several years, and did not want to become dependent on something or other for the pain. Mostly I could put up with it, but when I overdid an activity, such as carpentry, or car repair, or such, then I would surely pay for it the next day. At times I found it difficult to even clean a dozen fish, and so I began limiting many of my favorite activites... Last year, during my annual physical, my doctor made the suggestion that I might want to consider using Ultram ER on a trial basis. I, as per usual, declined with the same old excuse that I didn't want to get addicted to something, just so I could do things I used to do. Well, my wife chimed in, stating that I was to the point of doing little or nothing anymore because so many things tended to make me hurt. So, why not give a try for just one month, and see how it went. I finally agreed. I filled the scrip for a months supply, and after about a week my sister happened to ask how I was feeling, not knowing I was on a new medication. It was then that I realized that my hands had not hurt for a day or two... WOW, was I ever surprised a the realization!!! So, I have know been on ULTRAM ER for about 50 weeks, and I am doing many of the things I used to do, and suffer little, if any, from the activity, unless I totally overdo it. My friends even have noticed how much better I seem to be, and how much more I can do without complaining or bellyaching about the hurt. It has been a real godsend to me. And I would suggest others who may not want to get "hooked" try it - it's great!!!Read More Read Less